In order to improve the quality and progress of the project, the clinical operation adopts the project team responsibility system, the project team in Beijing leads the project management, and the resident project teams assists the project team in Beijing in the central management of the region. Leadingpharm has stationed clinical trial technicians in all provinces except Tibet and Qinghai, and established clinical offices in major cities in China, such as Shanghai, Guangzhou, Shijiazhuang, Wuhan, Changsha, Hangzhou, Taiyuan, Zhengzhou, Shenyang, Xi'an and Tianjin.